2020 Publications
Publications
January 1, 2020 through December 31, 2020
updated 8.31.2020
- Sifat AE, Nozohouri S, Villalba H, Vaidya B, Abbruscato TJ. The Role of Smoking and Nicotine in the Transmission and Pathogenesis of COVID-19. J Pharmacol Exp Ther. 2020 Dec;375(3):498-509. doi: 10.1124/jpet.120.000170. Epub 2020 Oct 8.PMID: 33033170
- Nozohouri S, Noorani B, Al-Ahmad A, Abbruscato TJ. Estimating Brain Permeability Using In Vitro Blood-Brain Barrier Models. Methods Mol Biol. 2020 Aug 14. doi: 10.1007/7651_2020_311. Online ahead of print.PMID: 32789777
- Ronak Patel, Snehal Raut, Abraham Al-Ahmad et al. Induced pluripotent stem cells derived brain endothelial cells from patients suffering from familial form of Alzheimer’s disease display impaired barrier function and cell metabolism.13 January 2020, PREPRINT (Version 2) available at Research Square [+https://doi.org/10.21203/rs.2.18501/v2+].Tanya Chhibber, Sounak Bagchi,
- Behnaz Lahooti, Angela Verma, Abraham Al-Ahmad, Manash K. Paul, Gurudutt Pendyala,
Rahul Dev Jayant. CNS organoids: an innovative tool for neurological disease modeling and drug neurotoxicity
screening. Drug Discovery Today. Volume 25, Issue 2, 2020, Pages 456-465. ISSN 1359-6446, https://doi.org/10.1016/j.drudis.2019.11.010.
(http://www.sciencedirect.com/science/article/pii/S1359644619304520) - Nozohouri S, Noorani B, Al-Ahmad A, Abbruscato TJ. Estimating Brain Permeability Using In Vitro Blood-Brain Barrier Models. Methods Mol Biol. 2020 Aug 14. doi: 10.1007/7651_2020_311. Online ahead of print.PMID: 32789777
- Noorani B, Chowdhury EA, Alqahtani F, Ahn Y, Patel D, Al-Ahmad A, Mehvar R, Bickel U. LC-MS/MS-based in vitro and in vivo investigation of blood-brain barrier integrity by simultaneous quantitation of mannitol and sucrose. Fluids Barriers CNS. 2020 Oct 14;17(1):61. doi: 10.1186/s12987-020-00224-1.PMID: 33054801
- Patel J, Chowdhury E, Noorani B, Bickel U, Huang J. Isoflurane increases cell membrane fluidity significantly at clinical concentrations. Biochimica et biophysica acta. Biomembranes 2020; 1862 (2) :183140.
- Noorani B, Chowdhury EA, Alqahtani F, Ahn Y, Patel D, Al-Ahmad A, Mehvar R, Bickel U. LC-MS/MS-based in vitro and in vivo investigation of blood-brain barrier integrity by simultaneous quantitation of mannitol and sucrose. Fluids Barriers CNS. 2020 Oct 14;17(1):61. doi: 10.1186/s12987-020-00224-1.PMID: 33054801
- Ashraf MS, Gaur S, Bushen OY, Chopra T, Chung P, Clifford K, Hames E, Hertogh CMPM, Krishna A, Mahajan D, Mehr DR0, Nalls V, Rowe TA, Schweon SJ, Sloane PD, Trivedi KK, van Buul LW, Jump RLP; Infection Advisory Subcommittee for AMDA—The Society of Post-Acute and Long-Term Care Medicine. Diagnosis, Treatment, and Prevention of Urinary Tract Infections in Post-Acute and Long-Term Care Settings: A Consensus Statement From AMDA's Infection Advisory Subcommittee. J Am Med Dir Assoc. 2020 Jan;21(1):12-24.e2. doi: 10.1016/j.jamda.2019.11.004.
- In vitro modeling of the neurovascular unit: advances in the field. Bhalerao A, Sivandzade F, Archie SR, Chowdhury EA, Noorani B, Cucullo L. Fluids Barriers CNS. 2020 Mar 16;17(1):22. doi: 10.1186/s12987-020-00183-7. Review. PMID: 32178700
- Sivandzade F., Alqahtani F., Sifat A., Cucullo L. Cerebrovascular and neurological impact of chronic smoking on post-traumatic brain injury outcome and recovery: an in vivo study. Journal of Neuroinflammation, 2020. 17(1): p. 133.
- Sivandzade F., Alqahtani F., Cucullo L. Traumatic Brain Injury and Blood-Brain Barrier: Underlying Pathophysiological Mechanisms and the Influence of Cigarette Smoking as a Premorbid Condition. Int. J. Mol. Sci. 2020, 21(8), 2721.
- Rolph D and Das H. Transcriptional regulation of osteoclastogenesis: the emerging
role of KLF2. Frontiers in Immunology 2020. 13 May, Vol 11, article 937.
(IF: 4.72) - Maity J, Deb M, Greene C, Das H. KLF2 regulates dental pulp-derived stem cell differentiation through the induction of mitophagy and altering mitochondrial metabolism. Redox biology 2020; 36 :101622.
- Rolph D, Deb M, Kanji S, Greene C, Das M, Joseph M, Aggarwal R, Leblebicioglu B, Das H. Ferutinin directs dental pulp-derived stem cells towards the osteogenic lineage by epigenetically regulating canonical Wnt signaling. Biochimica et biophysica acta. Molecular basis of disease 2020; 1866 (4) :165314.
- Joseph M, Das M, Kanji S, Lu J, Aggarwal R, Chakraborty D, Sarkar C, Yu H, Mao H, Basu S, Pompili V, Das H. Corrigendum to "Retention of stemness and vasculogenic potential of human umbilical cord blood stem cells after repeated expansions on PES-nanofiber matrices" [Biomaterials 35 (2014) 8566-8575]. Biomaterials 2020; 231 :119661.
- Md Ashraf-Uz-Zaman, Sadisna Shahi, Racheal Akwii, Md Sanaullah Sajib, Mohammad Jodeiri Farshbaf, Raja Reddy Kallem, William Putnam, Wei Wang, Ruiwen Zhang, Karina Alvina, Paul C Trippier, Constantinos M Mikelis, Nadezhda A German. Design, synthesis and structure-activity relationship study of novel urea compounds as FGFR1 inhibitors to treat metastatic triple-negative breast cancer. Eur J Med Chem. 2020 Sep 24;209:112866. doi: 10.1016/j.ejmech.2020.112866.
- Ashraf-Uz-Zaman M, Bhalerao A, Mikelis CM, Cucullo L, German NA. Assessing the Current State of Lung Cancer Chemoprevention: A Comprehensive Overview. Cancers (Basel). 2020 May 17;12(5):1265. doi: 10.3390/cancers12051265.PMID: 32429547
- Jayaraman S, Al Shoyaib A, Kocot J, Villalba H, Alamri FF, Rashid M, Wangler NJ, Chowdhury EA, German N, Arumugam TV, Abbruscato TJ, Karamyan VT. Peptidase neurolysin functions to preserve the brain after ischemic stroke in male mice. J Neurochem. 2020 Apr;153(1):120-137. doi: 10.1111/jnc.14864. Epub 2019 Oct 22.PMID: 31486527
- Krystal K. Haase, Erica F. Crannage, Patricia L. Orlando, Mary Lee , Jay L. Martello, Pamela L. Stamm, Kurt A. Wargo, Katie L. Kiser, Megan E. Fleischman. Pharmacy practice faculty and preceptor development. Am Coll Clin Pharm. 31 March 2020; 1–17.
- Eichmeyer J, Rogers S, Formea CM, Giri J, Jones JS, Schnettler E, Schmidlen T, Glogowski E, Kurz RN. PARC report: a perspective on the state of clinical pharmacogenomics testing. Pharmacogenomics. 2020 Jul;21(11):809-820. doi: 10.2217/pgs-2019-0193. Epub 2020 Jul 8.PMID: 32635876
- L Rogers S, Keeling NJ, Giri J, Gonzaludo N, Jones JS, Glogowski E, Formea CM. PARC report: a health-systems focus on reimbursement and patient access to pharmacogenomics testing. Pharmacogenomics. 2020 Jul;21(11):785-796. doi: 10.2217/pgs-2019-0192. Epub 2020 Aug 4.PMID: 32748688
- Jayaraman S, Al Shoyaib A, Kocot J, Villalba H, Alamri F, Rashid M, Wangler N, Chowdhury E, German N, Arumugam T, Abbruscato T, Karamyan V. Peptidase neurolysin functions to preserve the brain after ischemic stroke in male mice. Journal of neurochemistry 2020; 153 (1) :120-137.
- Sifat A, Nozohouri S, Villalba H, Al Shoyaib A, Vaidya B, Karamyan V, Abbruscato T. Prenatal electronic cigarette exposure decreases brain glucose utilization and worsens outcome in offspring hypoxic-ischemic brain injury. Journal of neurochemistry 2020; 153 (1) :63-79.
- Syeara N, Alamri F, Jayaraman S, Lee P, Karamyan S, Arumugam T, Karamyan V. Motor deficit in the mouse ferric chloride-induced distal middle cerebral artery occlusion model of stroke. Behavioural brain research 2020; 380 :112418.
- Markiewski MM, Daugherity E, Reese B, Karbowniczek M. The Role of Complement in Angiogenesis. Antibodies (Basel). 2020 Dec 1;9(4):67. doi: 10.3390/antib9040067. PMID: 33271774
- Wooster AL, Girgis LH, Brazeale H, Anderson TS, Wood LM, Lowe DB. Dendritic cell vaccine therapy for colorectal cancer. Pharmacol Res. 2021 Feb;164:105374. doi: 10.1016/j.phrs.2020.105374. Epub 2020 Dec 28.PMID: 33348026
- Markiewski MM, Daugherity E, Reese B, Karbowniczek M. The Role of Complement in Angiogenesis. Antibodies (Basel). 2020 Dec 1;9(4):67. doi: 10.3390/antib9040067. PMID: 33271774
- Ashraf-Uz-Zaman M, Bhalerao A, Mikelis C, Cucullo L, German N. Assessing the Current State of Lung Cancer Chemoprevention: A Comprehensive Overview. Cancers 2020; 12 (5) .
- Stratman A, Farrelly O, Mikelis C, Miller M, Wang Z, Pham V, Davis A, Burns M, Pezoa S, Castranova D, Yano J, Kilts T, Davis G, Gutkind J, Weinstein B. Antiangiogenic effects of VEGF stimulation on endothelium deficient in phosphoinositide recycling. Nature communications 2020; 11 (1) :1204.
- Srivastava S, Zahra F, Gupta N, Tullar P, Mikelis C. Low Dose of Penfluridol Inhibits VEGF-Induced Angiogenesis. International journal of molecular sciences 2020; 21 (3) .
- Md Ashraf-Uz-Zaman, Sadisna Shahi, Racheal Akwii, Md Sanaullah Sajib, Mohammad Jodeiri Farshbaf, Raja Reddy Kallem, William Putnam, Wei Wang, Ruiwen Zhang, Karina Alvina, Paul C Trippier, Constantinos M Mikelis, Nadezhda A German. Design, synthesis and structure-activity relationship study of novel urea compounds as FGFR1 inhibitors to treat metastatic triple-negative breast cancer. Eur J Med Chem. 2020 Sep 24;209:112866. doi: 10.1016/j.ejmech.2020.112866.
- Md Ashraf-Uz-Zaman, Sadisna Shahi, Racheal Akwii, Md Sanaullah Sajib, Mohammad Jodeiri Farshbaf, Raja Reddy Kallem, William Putnam, Wei Wang, Ruiwen Zhang, Karina Alvina, Paul C Trippier, Constantinos M Mikelis, Nadezhda A German. Design, synthesis and structure-activity relationship study of novel urea compounds as FGFR1 inhibitors to treat metastatic triple-negative breast cancer. Eur J Med Chem. 2020 Sep 24;209:112866. doi: 10.1016/j.ejmech.2020.112866.
- Horyna TJ, Jimenez R, McMurry L, Buscemi D, Cherry B, Seifert CF. An Evaluation of Interprofessional Patient Navigation Services in High Utilizers at a County Tertiary Teaching Health System. J Healthc Manag. 2020 Jan-Feb;65(1):62-70. PMID: 31913241 doi: 10.1097/JHM-D-19-00123.
- Punganuru SR, Artula V, Zhao W, Rajaei M, Deokar H, Zhang R, Buolamwini JK, Srivenugopal KS, Wang W. Targeted Brain Tumor Therapy by Inhibiting the MDM2 Oncogene: In Vitro and In Vivo Antitumor Activity and Mechanism of Action. Cells. 2020 Jul 1;9(7):1592. doi: 10.3390/cells9071592.PMID: 32630235
- Punganuru SR, Artula V, Zhao W, Rajaei M, Deokar H, Zhang R, Buolamwini JK, Srivenugopal KS, Wang W. Targeted Brain Tumor Therapy by Inhibiting the MDM2 Oncogene: In Vitro and In Vivo Antitumor Activity and Mechanism of Action. Cells. 2020 Jul 1;9(7):1592. doi: 10.3390/cells9071592.PMID: 32630235
- Wooster AL, Girgis LH, Brazeale H, Anderson TS, Wood LM, Lowe DB. Dendritic cell vaccine therapy for colorectal cancer. Pharmacol Res. 2021 Feb;164:105374. doi: 10.1016/j.phrs.2020.105374. Epub 2020 Dec 28.PMID: 33348026
Published Book Chapters/ Editorials/ Commentaries
- Blaszczyk AT, Mahan RJ. Alzheimer’s Disease: Oh Right! I Keep Forgetting. In: Schwinghammer TL, Koehler JM, Borchert JS, Slain D, Park SK, eds. Pharmacotherapy Casebook: A Patient-Focused Approach, 11th Edition. New York, NY: McGraw-Hill. 2020.
- Blaszczyk AT, Mahan RJ. Alzheimer’s Disease: Oh Right! I Keep Forgetting. In: Schwinghammer TL, Koehler JM, Borchert JS, Slain D, Park SK, eds. Pharmacotherapy Casebook: A Patient-Focused Approach, 11th Edition. New York, NY: McGraw-Hill. 2020.
Publication Archives
Patents / Technologies
- # WO 2020/018868 A1 - Corneal epithelial cells and their products for treating corneal diseases. Date: 1.23.2020 (Hiranmoy Das and S.W. Rush)
- #WO 2019 / 241462 A1 - Stem cells for the treatment for conditions and diseases. Date: 12-19-2019 (Hiranmoy Das)
- #US 2019 / 0091310 A - Nonreleased IL-12 for therapy of cancer. Date: 3.28.2019 (S.E. Wright and Hiranmoy Das)
- #62/725444 - Enhancers of Neurolysin Activity (Vardan T. Karamyan, Paul C. Trippier, Thomas J. Abbruscato, David A. Ostrov, Srinidhi Jayaraman)
- #62/670479 - Method of treating cancer with Atpenin A5 derivatives. (Paul C. Trippier and Paul S. Brookes)
- #PCT/US18/42009 - Functionalized Pyridine Carbamates with
Enhanced Neuroprotective Activity (Paul C. Trippier, Nihar Kinarivala and Rose-Mary Boustany) - #WO 2018148721 A1 - Phenylacrylic acid derivatives as highly selective AKR1C3 inhibitors, methods of use and their preparation. (Paul C. Trippier, Kshitij Verma, Tianzhu Zang and Trevor Penning)
- #62/700,639 - Corneal Epithelial Cells and Their Products for Treating Corneal Diseases. (Hiranmoy Das)
- #PCT/US 2018: 60763 - Composition and methods for treating cancer. (Sanjay K. Srivastava)
- #62/532624 - Functionalized Pyridine Carbamates with enhanced neuroprotective activity (Paul C. Trippier)
- #62/458267 - Highly selective AKR1C3 inhibitors and methods of use thereof (Paul C. Trippier)
- #62/422797 - Potent and selective peroxisome proliferator-activated Receptor beta/delta agonists (Paul C. Trippier)
- PCT/US2016 #036002 - Inhibitors of Mcl-1 as drugs to overcome resistance to BRAF inhibitors and MEK inhibitors (Sanjay K. Srivastava)
- WO2015120254 A1 - Disulfiram compositions and treatments for brain tumors (Kalkunte S. Srivenugopal)
- US 62/268,882. - Small molecule allosteric potentiators of peptidase neurolysin (Vardan T. Karamyan)
- #62/172,327 - Inhibitors of Mcl-1 as drugs to overcome resistance to BRAF inhibitors and MEK inhibitors (Sanjay K. Srivastava)
- # 62/189,377 - Formulations of piperlongumine for oral and topical application for prevention and treatment of melanoma (Sanjay K. Srivastava)
- #62026970 - Overcoming Chemotherapeutic Agent Resistance in Cancer by Inhibiting Mcl-1 (Sanjay K. Srivastava)
- US20140134241 A1 - WO2012129520A1 - TCR Mimic Antibodies as Vascular Targeting Tools (John Weidanz & Ulrich Bickel)
- WO2015095002 A1 - CA2932480 A1 - CN105916882AR - Anti-RON Monoclonal Antibodies as a Cytotoxic Drug Delivery System for Targeted Cancer Therapy (Ming-Hai Wang)
- WO2016049453 A1 - Cancer Treatment Utilizing SP-141 to Bind with MDM2 and Act as an Inhibitor of MDM2 Expression (Ruiwen Zhang & Wei Wang)
- WO2014210411 A1 - Histone deacetylase inhibitors and methods of use (Sanjay K. Srivastava)
- #61973672 - Overcoming vemurafenib resistance in metastatic cancers (Sanjay K. Srivastava)
- #62026970 - Overcoming chemotherapeutic agent resistance in cancer by inhibiting Mcl-1 (Sanjay K. Srivastava)
- WO2013067305 A1 - Media compositions for promoting bacterial and fungal growth (Mark Lyte)
- #61840751 - Histone deacetylase inhibitors and methods of use (Sanjay K. Srivastava)
- WO2013/074820 - Immunogenic tumor associated stromal cell antigen peptides and methods of their use. (WJ Storkus, A. Bose, JL Taylor, X Zhao, DB Lowe)
- US20090087517 A1 - WO2007052081 A3 - Bacterial growth enhancer (Mark Lyte)
- US20090118202 A1 - Compositions and methods of treating hypertension with tannin complexes (Thomas Thekkumkara)
- US20140065708 A1 - Antibodies as t cell receptor mimics, methods of production and uses thereof (Jon A. Weidanz)